|
@@ -0,0 +1,200 @@
|
|
|
+<?php
|
|
|
+
|
|
|
+/*
|
|
|
+ * By adding type hints and enabling strict type checking, code can become
|
|
|
+ * easier to read, self-documenting and reduce the number of potential bugs.
|
|
|
+ * By default, type declarations are non-strict, which means they will attempt
|
|
|
+ * to change the original type to match the type specified by the
|
|
|
+ * type-declaration.
|
|
|
+ *
|
|
|
+ * In other words, if you pass a string to a function requiring a float,
|
|
|
+ * it will attempt to convert the string value to a float.
|
|
|
+ *
|
|
|
+ * To enable strict mode, a single declare directive must be placed at the top
|
|
|
+ * of the file.
|
|
|
+ * This means that the strictness of typing is configured on a per-file basis.
|
|
|
+ * This directive not only affects the type declarations of parameters, but also
|
|
|
+ * a function's return type.
|
|
|
+ *
|
|
|
+ * For more info review the Concept on strict type checking in the PHP track
|
|
|
+ * <link>.
|
|
|
+ *
|
|
|
+ * To disable strict typing, comment out the directive below.
|
|
|
+ */
|
|
|
+
|
|
|
+declare(strict_types=1);
|
|
|
+
|
|
|
+class ProteinTranslationTest extends PHPUnit\Framework\TestCase
|
|
|
+{
|
|
|
+ private ProteinTranslation $translater;
|
|
|
+
|
|
|
+ public static function setUpBeforeClass(): void
|
|
|
+ {
|
|
|
+ require_once 'ProteinTranslation.php';
|
|
|
+ }
|
|
|
+
|
|
|
+ public function setUp(): void
|
|
|
+ {
|
|
|
+ $this->translater = new ProteinTranslation();
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testEmptyRnaSequence(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals([], $this->translater->getProteins(''));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testMethionineRnaSequence(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Methionine'], $this->translater->getProteins('AUG'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testPhenylalanineRnaSequenceOne(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Phenylalanine'], $this->translater->getProteins('UUU'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testPhenylalanineRnaSequenceTwo(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Phenylalanine'], $this->translater->getProteins('UUC'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testLeucineRnaSequenceOne(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Leucine'], $this->translater->getProteins('UUA'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testLeucineRnaSequenceTwo(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Leucine'], $this->translater->getProteins('UUG'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testSerineRnaSequenceOne(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Serine'], $this->translater->getProteins('UCU'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testSerineRnaSequenceTwo(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Serine'], $this->translater->getProteins('UCC'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testSerineRnaSequenceThree(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Serine'], $this->translater->getProteins('UCA'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testSerineRnaSequenceFour(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Serine'], $this->translater->getProteins('UCG'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testTyrosineRnaSequenceOne(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Tyrosine'], $this->translater->getProteins('UAU'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testTyrosineRnaSequenceTwo(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Tyrosine'], $this->translater->getProteins('UAC'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testCysteineRnaSequenceOne(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Cysteine'], $this->translater->getProteins('UGU'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testCysteineRnaSequenceTwo(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Cysteine'], $this->translater->getProteins('UGC'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testTryptophanRnaSequence(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Tryptophan'], $this->translater->getProteins('UGG'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testStopCodonRnaSequenceOne(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals([], $this->translater->getProteins('UAA'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testStopCodonRnaSequenceTwo(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals([], $this->translater->getProteins('UAG'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testStopCodonRnaSequenceThree(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals([], $this->translater->getProteins('UGA'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testToCodonsTranslateToProteins(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Phenylalanine', 'Phenylalanine'], $this->translater->getProteins('UUUUUU'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testToDifferentCodonsTranslateToProteins(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Leucine', 'Leucine'], $this->translater->getProteins('UUAUUG'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testTranslateRnaStrandToCorrectProteinList(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(
|
|
|
+ ['Methionine', 'Phenylalanine', 'Tryptophan'],
|
|
|
+ $this->translater->getProteins('AUGUUUUGG')
|
|
|
+ );
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testTranslationStopsIfStopCodonAtBeginningOfSequence(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals([], $this->translater->getProteins('UAGUGG'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testTranslationStopsIfStopCodonAtEndOfTwoCodonSequence(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Tryptophan'], $this->translater->getProteins('UGGUAG'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testTranslationStopsIfStopCodonAtEndOfThreeCodonSequence(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Methionine', 'Phenylalanine'], $this->translater->getProteins('AUGUUUUAA'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testTranslationStopsIfStopCodonInMiddleOfThreeCodonSequence(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Tryptophan'], $this->translater->getProteins('UGGUAGUGG'));
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testTranslationStopsIfStopCodonInMiddleOfSixCodonSequence(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(
|
|
|
+ ['Tryptophan', 'Cysteine', 'Tyrosine'],
|
|
|
+ $this->translater->getProteins('UGGUGUUAUUAAUGGUUU')
|
|
|
+ );
|
|
|
+ }
|
|
|
+
|
|
|
+ public function invalidCodonDataProvider(): array
|
|
|
+ {
|
|
|
+ return [
|
|
|
+ 'Non-existing' => ['AAA'],
|
|
|
+ 'Unknown' => ['XYZ'],
|
|
|
+ 'Incomplete' => ['AUGU'],
|
|
|
+ ];
|
|
|
+ }
|
|
|
+
|
|
|
+ /**
|
|
|
+ * @dataProvider invalidCodonDataProvider
|
|
|
+ */
|
|
|
+ public function testTranslateFailsForInvalidCodons(string $rna): void
|
|
|
+ {
|
|
|
+ $this->expectException(InvalidArgumentException::class);
|
|
|
+ $this->expectExceptionMessage('Invalid codon');
|
|
|
+ $this->translater->getProteins($rna);
|
|
|
+ }
|
|
|
+
|
|
|
+ public function testTranslatePassesIfStopCodeBeforeIncompleteSequence(): void
|
|
|
+ {
|
|
|
+ $this->assertEquals(['Phenylalanine', 'Phenylalanine'], $this->translater->getProteins('UUCUUCUAAUGGU'));
|
|
|
+ }
|
|
|
+}
|